Fig. 4
UTX is essential for CRC growth in vivo. A total of 2 * 106 cells were subcutaneously injected into the left dorsal flank per nude mouse. a UTX knockdown suppressed xenograft tumour growth of HCT116 cells in vivo (n = 5). Images of tumours are from all mice in each group. b Tumour volume was measured. c Tumour weight was measured. d Representative photographs of UTX and Ki-67 IHC staining in the indicated tumours. Data are shown as the mean ± SD. (*p < 0.05, **p < 0.01, ***p < 0.001, Student’s t-test)