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Fig. 2 | Cancer Cell International

Fig. 2

From: Low expression of SPARC in gastric cancer-associated fibroblasts leads to stemness transformation and 5-fluorouracil resistance in gastric cancer

Fig. 2

Effect of GCAF-derived SPARC on 3D gastric tumour growth and the 5-FU response in vitro. Tumour growth: a Confocal laser scanning microscopy of 3D gastric cancer tumour spheres (the scale bar was adjusted according to the actual sphere sizes). b Comparison of the sphere diameters in SGC-7901 cells. c Comparison of the sphere diameters in BGC-823 cells. 5-FU response: d Confocal laser scanning microscopy of 3D gastric cancer tumour spheres (the scale bar was adjusted according to the actual sphere sizes). e Comparison of the sphere diameters in SGC-7901 cells. f Comparison of the sphere diameters in BGC-823 cells. *P < 0.05, **P < 0.01

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