Table 1 Correlations between SPARC staining and clinicopathological features of patients with gastric cancer
Parameter | No. | Stromal SPARC expression | P value | Cancer SPARC expression | P value | ||
|---|---|---|---|---|---|---|---|
High | Low | High | Low | ||||
Gender | |||||||
 Female | 36 | 14 (39%) | 22 (61%) | 0.257 | 3 (8%) | 33(92%) | 0.717 |
 Male | 156 | 77 (49%) | 79 (51%) |  | 19 (12%) | 137 (88%) |  |
Age | |||||||
 < 70 | 142 | 64 (45%) | 78 (55%) | 0.277 | 18 (13%) | 124 (87%) | 0.372 |
 ≥ 70 | 50 | 27 (54%) | 23 (46%) |  | 4 (8%) | 46 (92%) |  |
Histological type | |||||||
 Adenocarcinoma | 153 | 67 (44%) | 86 (56%) | 0.048 | 16 (10%) | 137 (90%) | 0.561 |
 Other type | 39 | 24 (62%) | 15 (38%) |  | 6 (15%) | 33 (85%) |  |
Grade | |||||||
 Well differentiated | 18 | 12 (67%) | 6 (33%) | 0.003 | 5 (28%) | 13 (72%) | 0.074 |
 Moderately differentiated | 67 | 37 (55%) | 30 (45%) |  | 6 (9%) | 61 (91%) |  |
 Poorly differentiated | 94 | 34 (36%) | 60 (64%) |  | 7 (7%) | 87 (93%) |  |
Tumor location | |||||||
 Fundus-cardia | 26 | 17 (65%) | 9 (35%) | 0.195 | 1 (4%) | 25 (96%) | 0.375 |
 Body | 28 | 21 (75%) | 7 (25%) |  | 8 (29%) | 20 (71%) |  |
 Antrum | 54 | 31 (57%) | 23 (43%) |  | 5 (9%) | 49 (91%) |  |
 Diffused | 12 | 5 (42%) | 7 (58%) |  | 0 (0) | 12 (100%) |  |
Degree of invasion | |||||||
 T1 | 5 | 3 (60%) | 2 (40%) | 0.907 | 2 (40%) | 3 (60%) | 0.825 |
 T2 | 25 | 16(64%) | 9 (36%) |  | 2 (8%) | 23 (92%) |  |
 T3 | 59 | 35 (59%) | 24 (41%) |  | 6 (10%) | 53 (90%) |  |
 T4 | 31 | 20 (65%) | 11 (35%) |  | 4 (13%) | 27 (87%) |  |
Lymph node metastasis | |||||||
 0 | 27 | 20 (74%) | 7 (26%) | 0.277 | 6 (22%) | 21 (78%) | 0.237 |
 1–2 | 18 | 9 (50%) | 9 (50%) |  | 1 (6%) | 17 (94%) |  |
 3–6 | 34 | 22 (65%) | 12 (35%) |  | 3 (9%) | 31 (91%) |  |
 7 or more | 41 | 23 (56%) | 18 (44%) |  | 4 (10%) | 37 (90%) |  |
Cancer embolus | |||||||
 Yes | 50 | 30 (60%) | 20 (40%) | 0.751 | 4 (8%) | 46 (92%) | 0.290 |
 No | 70 | 44 (63%) | 26 (37%) |  | 10 (14%) | 60 (86%) |  |
Stage | |||||||
 I | 41 | 17 (41%) | 24 (59%) | 0.063 | 6 (15%) | 35 (85%) | 0.248 |
 II | 77 | 32 (42%) | 45 (58%) |  | 10 (13%) | 67 (87%) |  |
 III | 74 | 42 (57%) | 32 (43%) |  | 6 (8%) | 68 (92%) |  |