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Table 2 Univariate and multivariate Cox multiple regression analysis of overall survival after surgery in patients with gastric cancer

From: Low expression of SPARC in gastric cancer-associated fibroblasts leads to stemness transformation and 5-fluorouracil resistance in gastric cancer

Parameter

Univariate

Multivariate

HR

95% CI

P value

HR

95% CI

P value

SPARC in GCAFs

 Positive

0.502

0.279–0.904

0.016

0.418

0.207–0.841

0.015

SPARC in cancer cells

 Positive

1.556

0.561–4.315

0.304

2.489

0.671–9.238

0.173

Histological type

 Adenocarcinoma

0.755

0.4043–1.409

0.349

0.744

0.353–1.570

0.438

Grade

 Poorly differentiated

1.512

0.815–2.804

0.180

1.358

0.710–2.597

0.355

Degree of invasion

 Deep

2.361

1.259–4.426

0.030

1.714

0.726–4.043

0.219

Lymph node metastasis

 Positive

3.708

1.927–7.136

0.007

1.640

0.523–5.140

0.396

Cancer embolus

 Positive

1.847

1.025–3.329

0.032

1.543

0.798–2.982

0.197