Fig. 3
From: Knockdown of PKM2 enhances radiosensitivity of cervical cancer cells
PKM2 influenced DNA damage repair. a, b Different group of cells was subjected to IR. 1, 12, and 24 h after IR, cells were fixed and immunostained for γ-H2AX foci. The numbers of γ-H2AX foci at all time points were measured in both HeLa and SiHa cells. Untreated cells were used as the negative control. Representative images are presented here (400×). c, d Knockdown of PKM2 significantly increased the numbers of γ-H2AX foci after different doses of irradiation in both HeLa and SiHa cells. Data represent three independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001