Fig. 8From: Bursopentin (BP5) induces G1 phase cell cycle arrest and endoplasmic reticulum stress/mitochondria-mediated caspase-dependent apoptosis in human colon cancer HCT116 cellsCaspase-dependent apoptosis was stimulated by BP5 in HCT116 cells. Cells were incubated with 20 μM zVAD-fmk for 2 h, then the cultures were treated with 8 mM BP5 for another 24 h. a Quantification of the cell viability determined by CCK8 assay. b Quantification of apoptotic cells detected by flow cytometry. The quantitative data shown are mean ± SD (n = 3) (**p < 0.01, ***p < 0.001)Back to article page