Fig. 1
From: Decreased SATB1 expression promotes AML cell proliferation through NF-κB activation
SATB1 expression was decreased both in newly diagnosed AML patients and AML cell lines compared to healthy donors, but increased after patients achieved CR. a SATB1 mRNA expression was lower in 52 newly diagnosed AML patients compared to 38 healthy donors (P < 0.0001). b SATB1 mRNA expression was increased in 29 CR samples compared to their initial AML samples (P = 0.0306). c SATB1 expression in AML based on FAB classification including 3 cases of mixed AML. d SATB1 mRNA expression was lower in 4 AML cell lines: HL-60, NB4, HEL and THP-1 (P < 0.0001). e, f Western blotting showed that SATB1 exhibited highest expression in HL-60 cells among 4 AML cell lines (P < 0.0001)