Fig. 3
From: Decreased SATB1 expression promotes AML cell proliferation through NF-κB activation
Knockdown of SATB1 promoted tumorigenicity in nude mice. a HL-60 SATB1-shRNA1 and HL-60 CTR cells (1 × 107) were injected subcutaneously in SATB1-shRNA1 and CTR mice, respectively. Tumor was formed in 4 mice in each group. All mice were executive 3 weeks after injection. b Tumor size was measured everyday and the result showed that tumor volume of SATB1-shRNA1 was larger compared to CTR mice. c Tumor weight showed a significant increase in SATB1 shRNA mice (P = 0.0286)