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Table 2 Multivariate analyses of prognostic factors for overall survival in the FUSCC

From: Adjuvant chemotherapy for rectal cancer with complete pathological response (pCR) may not be necessary: a pooled analysis of 5491 patients

Variables

Cox proportional hazards

Hazard ratio

95% CI

p value

Adjuvant chemotherapy

0.678

 No

1 (reference)

 

 Yes

0. 739

0.176–3.093

Gender

0.019

 Female

1 (reference)

 

 Male

0.081

0.010–0.658

Age

1.058

0.985–1.135

0.12

Clinical T stage

0.926

 T2

1 (reference)

 

 T3/4

0. 937

0.234–3.747

Clinical N sage

0.697

 N0

1 (reference)

 

 N1–2

0.753

0.180–3.150

CRM

0.122

 Negative

1 (reference)

 

 Positive

3.539

0.714–17.539

EMVI

0.281

 Negative

1 (reference)

 

 Positive

0.316

0.039–2.568

Operation

0.361

 AR

1 (reference)

 

 APR

1.949

0.466–8.159

Lymph node examined

0.064

 ≤ 12

1 (reference)

 

 > 12

0.854

0.722–1.009

  1. CRM indicates circumferential resection margin; EMVI, extramural venous invasion; AR, anterior resection; APR, abdominoperineal resection