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Table 3 Multivariate analyses of prognostic factors for cancer disease-free survival in the FUSCC

From: Adjuvant chemotherapy for rectal cancer with complete pathological response (pCR) may not be necessary: a pooled analysis of 5491 patients

Variables

Cox proportional hazards

Hazard ratio

95% CI

p value

Adjuvant chemotherapy

0.855

 No

1 (reference)

 

 Yes

0.912

0.342–2.432

Gender

0.215

 Female

1 (reference)

 

 Male

1.340

0.844–2.127

Age

1.016

0.972–1.061

0.481

Clinical T stage

0.446

 T2

1 (reference)

 

 T3/4

0.697

0.275–1.766

Clinical N sage

0.401

 N0

1 (reference)

 

 N1–2

0.657

0.247–1.751

CRM

0.707

 Negative

1 (reference)

 

 Positive

1.194

0.474–3.010

EMVI

0.222

 Negative

1 (reference)

 

 Positive

0. 462

0.134–1.597

Operation

0.391

 AR

1 (reference)

 

 APR

1.503

0.593–3.809

Lymph node examined

0.381

 ≤ 12

1 (reference)

 

 > 12

0.406

0.054–3.049

  1. CRM, circumferential resection margin; EMVI, extramural venous invasion; AR, anterior resection; APR, abdominoperineal resection