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Table 5 Overview of baseline characteristics per included study

From: Adjuvant chemotherapy for rectal cancer with complete pathological response (pCR) may not be necessary: a pooled analysis of 5491 patients

Author

Shahab D

Zhou

Geva R

Gamaleldin M

Kuan FC

Kiran RP

Hu X

CAPIRCI C

Dossa F

Year

2017

2016

2014

2017

2017

2012

2019

2008

2018

Country

USA

China

Israel

USA

China

USA

China

Italy

Canada

Study design

Retrospective

Case control

Case control

Prospective control

Case control

Case control

Case control

Prospective sub-group

Retrospective

N

789/2102

19/21

35/17

47/83

114/145

14/34

115/56

127/439

667/667

Age (c/n)

57.2/61.2

54/54.1

60.9/68.7

55.9/60.6

56.7/61.8

50.5/55.5

54.5/57.6

62

56/57

Gender (male%)

56.8/61.2

36.8/76.2

68.5/47

57.4/67.5

59.6/66.2

50/73.5

67.8/57.8

67

56.8/55.5

cT-stage

 T1–2

110/348

2/2

1/2

NA

11/21

1/4

57/23

29

60/59

 T3–4

679/1754

17/19

31/14

NA

102/124

13/30

58/33

409

585/584

cN-stage

 N0

388/1224

6/7

23/12

25/48

33/52

9/22

66/31

NA

319/319

 N+

401/878

10/12

9/3

22/34

81/91

5/12

49/25

169

348/348

Surgery

 AR

565/1474

16/12

26/10

5/41

78/108

12/22

69/25

339

NA

 APR

183/511

3/9

9/7

42/13

15/16

2/12

46/31

100

NA

 Chemotherapy regimen

NA

Combined and single-agent

NA

NA

NA

NA

Combined and single-agent

Combined and single-agent

NA

  1. c/n, chemotherapy group vs. no-chemo group; NA, no available; AR, anterior resection; APR, abdominoperineal resection