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Fig. 3 | Cancer Cell International

Fig. 3

From: Overexpression of mircoRNA-137 inhibits cervical cancer cell invasion, migration and epithelial–mesenchymal transition by suppressing the TGF-β/smad pathway via binding to GREM1

Fig. 3

CC tissues presented with lower miR-137 expression, higher GREM1 expression and activated TGF-β1/smad pathway. a The expression of miR-137 and mRNA expression of GREM1, TGF-β1, Smad2, Smad3 and Smad4 in CC tissues detected by RT-qPCR normalized to adjacent tissues; b, c the protein expression of GREM1, TGF-β1, Smad2, Smad3 and Smad4 examined by Western blot assay normalized to β-actin; data were presented as mean ± standard deviation and analyzed by paired t-test; n = 109; *p < 0.05 vs. adjacent tissues. miR-137 microRNA-137, GREM1 gremlin-1, RT-qPCR reverse transcription quantitative polymerase chain reaction

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