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Fig. 7 | Cancer Cell International

Fig. 7

From: Overexpression of mircoRNA-137 inhibits cervical cancer cell invasion, migration and epithelial–mesenchymal transition by suppressing the TGF-β/smad pathway via binding to GREM1

Fig. 7

Overexpression of miR-137 reduces CC cell proliferation and colony formation by inhibiting GREM1. a The OD value of cells treated with miR-137 mimic, miR-137 inhibitor and/or siRNA-GREM1 at the different time point assessed by MTT assay; b colony formation rate of cells treated with miR-137 mimic, miR-137 inhibitor and/or siRNA-GREM1; c representative images of colony formation in cells treated with miR-137 mimic, miR-137 inhibitor and/or siRNA-GREM1; *p < 0.05 vs. the blank and NC groups; statistical data were presented as mean ± standard deviation; one-way analysis of variance was used for multi-group comparisons; the experiment was repeated 3 times independently. CC cervical cancer, GREM1 gremlin-1, miR-137 microRNA-137, MTT 3-(4,5-dimethylthiazol-2-Yl)-2,5-diphenyltetrazolium bromide

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Cancer Cell International

ISSN: 1475-2867

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