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Fig. 6 | Cancer Cell International

Fig. 6

From: Identification of hub genes and therapeutic drugs in esophageal squamous cell carcinoma based on integrated bioinformatics strategy

Fig. 6

a High expression of NDC80 was significantly associated with poor OS in ESCC patients, using a Kaplan–Meier curve and a log-rank test (Kaplan–Meier-plotter website; http://kmplot.com/analysis/). b The network contained 50 nodes, including 10 hub genes and the 40 most frequently altered neighbor genes. The relationships between 10 hub genes and drugs were also presented. c A visual summary across a set of ESCC (data from esophageal squamous cell carcinoma, TCGA, Provisional) showed the genetic alterations connected with the 10 hub genes which were altered in 24 (25%) of 96 sequenced cases/patients (96 total). d An overview of changes in the 10 hub genes in the genomics datasets of ESCC in TCGA database

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