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Fig. 4 | Cancer Cell International

Fig. 4

From: Mst1 overexpression combined with Yap knockdown augments thyroid carcinoma apoptosis via promoting MIEF1-related mitochondrial fission and activating the JNK pathway

Fig. 4

Mitochondrial fission is further enhanced by Mst1 overexpression in combination with Yap knockdown. a, b Immunofluorescence assay was used to observe the alteration of mitochondrial length using the mitochondrial antibody Tom-20. Adenovirus Mst1 (ad-Mst1) and shRNA against Yap (sh-Yap) were transfected into MDAT-32 cells. cg Proteins were isolated from MDAT-32 cells and then western blot was used to evaluate the levels of mitochondrial fission-related proteins. Adenovirus Mst1 (ad-Mst1) and shRNA against Yap (sh-Yap) were transfected into MDAT-32 cells. *p < 0.05 vs. control group, #p < 0.05 vs. ad-Mst1 group and/or sh-Yap group

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