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Table 2 Subgroup analysis of PD-L1 and OS, PFS in cervical cancer

From: Elevated PD-L1 expression predicts poor survival outcomes in patients with cervical cancer

Factors No. of studies Effects model HR (95% CI) p Heterogeneity I2(%) Ph
OS
 Total 7 Random 2.52 (1.09–5.83) 0.031 73 0.001
Ethnicity
 Asian 5 Fixed 4.77 (3.02–7.54) < 0.001 18 0.3
 Caucasian 2 Fixed 1.13 (0.68–1.88) 0.634 0 0.562
Sample size
 < 100 3 Fixed 5.01 (1.93–13.03) 0.001 0 0.471
 ≥ 100 4 Random 1.75 (0.55–5.59) 0.344 83.7 < 0.001
Treatment
 Surgery 5 Fixed 3.04 (1.42–6.48) 0.004 36.6 0.177
 Non-surgery 2 Random 2.29 (0.51–10.34) 0.28 93.6 < 0.001
PFS
 Total 3 Random 2.07 (0.52–8.23) 0.302 77.3 0.012
Ethnicity
 Asian 2 Fixed 4.78 (1.77–12.91) 0.002 28.7 0.236
 Caucasian 1 NA 1.02 (0.62–1.69) 0.939 NA NA
  1. OS, overall survival; PFS, progression-free survival; NA, not available