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Fig. 4 | Cancer Cell International

Fig. 4

From: Interaction of HE4 and ANXA2 exists in various malignant cells—HE4–ANXA2–MMP2 protein complex promotes cell migration

Fig. 4

Comparing the biological behaviors in cells with different expression levels of HE4 and ANXA2. a Cell cycles are detected by flow cytometry. * means the proportion of G1 phase of ES-2 is significantly less than that of HGC-27 (p < 0.05); b proliferation ability of different cells are detected by MTS. *and & mean the proliferation abilities of ES-2 and HT29 are significantly stronger than that of HGC-27 and HEK293 (p < 0.05); c adhesion ability of different cells are detected by adhesion test. * means the adhesion ability of ES-2 is significantly stronger than that of the others (p < 0.05); d migration ability of different cancer cells are detected by wound healing assay. * means the wound healing ability of ES-2 is stronger than that of HGC-27 and HT29 cells (p < 0.05); e invasion ability of different cancer cells are detected by matrigel-transwell assay. # means the invasion ability of ES-2 is stronger than that of HGC-27 and HT29 cells (p < 0.05)

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