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Fig. 5 | Cancer Cell International

Fig. 5

From: Interaction of HE4 and ANXA2 exists in various malignant cells—HE4–ANXA2–MMP2 protein complex promotes cell migration

Fig. 5

HE4–ANXA2–MMP2 protein complex work together to promote cell migration. a Immunoprecipitation of HE4 or ANXA2, and western blot detection of MMP2; b immunofluorescence detection of co-localization of ANXA2 and MMP2 in HEK293 cell. Green represents MMP2, red represents ANXA2, blue represents nucleus, and orange is the merged color of green and red; c western blot detection of Caov-3 cell model which was stably transfected with HE4 or ANXA2 gene or shRNA; d, e western blot detection and g migration detection after transfection and protein addition. 1 is control cells, 2 is HE4-silencing cells, 3 is HE4-silencing with recombinant ANXA2 addition. f Western blot detection of MMP2 with the change of ANXA2 in transfected Caov-3

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Cancer Cell International

ISSN: 1475-2867

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