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Fig. 9 | Cancer Cell International

Fig. 9

From: Mutual regulation of JAG2 and PRAF2 promotes migration and invasion of colorectal cancer cells uncoupled from epithelial–mesenchymal transition

Fig. 9

Correlation analysis between the migration/invasion-promoting effect of JAG2-rich exosomes and the Notch receptors. a, b Silencing of NOTCH1–4 by siRNA and the efficiency of siRNA silencing by real-time quantitative PCR and Western blot; c, d silencing NOTCH1–4 by siRNA could not effectively inhibit cell migration and invasion promoted by JAG2 exosomes. Data are the mean ± SD. of three independent experiments. *P < 0.05 versus control

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