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Fig. 1 | Cancer Cell International

Fig. 1

From: β-Asarone increases doxorubicin sensitivity by suppressing NF-κB signaling and abolishes doxorubicin-induced enrichment of stem-like population by destabilizing Bmi1

Fig. 1

β-Asarone inhibits proliferation and induces apoptosis. a Raji cells were treated with the indicated concentration of β-Asarone, cells counting assay was performed at the indicated time points. b Cells were treated with various concentration (from 1600 to 0.20 μM, each concentration was 1/2 of the previous one) of β-Asarone for 72 h. The proliferation was examined by cells counting assay. The IC50 were calculated by GraphPad Prism 6.0. c–e Raji cells were treated with the indicated concentration of β-Asarone for 72 h. Apoptosis was determined by the Annexin V-FITC/PI staining and flow cytometry analysis. Representative results were shown in c and statistical results were shown in d. The expression of apoptotic proteins was determined by western blot (e). The bar represents mean ± SD of three independent experiments (*p < 0.05, **p < 0.01, ***p < 0.001, the ANOVA test, followed by Least Significant Difference test, were used to make statistical comparisons)

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Cancer Cell International

ISSN: 1475-2867

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