Skip to main content
Fig. 3 | Cancer Cell International

Fig. 3

From: RETRACTED ARTICLE: LncRNA TUBA4B functions as a competitive endogenous RNA to inhibit gastric cancer progression by elevating PTEN via sponging miR-214 and miR-216a/b

Fig. 3

TUBA4B inhibits the oncogenic PI3K/AKT pathway via upregulation of PTEN. a The hierarchical clustering map showing the differentially expressed genes after TUBA4B overexpression. b Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of the differentially expressed genes after TUBA4B overexpression. c Gene Set Enrichment Analysis (GSEA) showing the negative correlation between TUBA4B and PI3K/AKT pathway. d, e Western blot analysis of the indicated protein expression in TUBA4B-overexpressing MGC-803 and HGC-27 cells. f–h. CCK-8 proliferative, transwell invasion and cell apoptosis assays in TUBA4B-overexpressing MGC-803 and HGC-27 cells after transfected with PTEN siRNA or constitutively-activated Akt1 (myr-AKT) vector. **p < 0.01, ***p < 0.001

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us