Skip to main content
Fig. 3 | Cancer Cell International

Fig. 3

From: Harmine suppresses hyper-activated Ras–MAPK pathway by selectively targeting oncogenic mutated Ras/Raf in Caenorhabditis elegans

Fig. 3

Screening of extracts of plant and animals reveals that the DCM and EtOAc fractions of P. harmala seed extracts inhibit the Muv phenotype in let-60(n1046gf). a 70% EtOH extract of P. harmala seeds suppresses the Muv phenotype in let-60(n1046gf). White arrows indicate pseudovulvas and black arrowheads indicate normal vulvas. Statistical analyses of the data are also shown. b TLC results showed that the 70% EtOH extract contained harmine. c Among five fractions, the DCM and EtOAc fractions of P. harmala significantly inhibit the Muv phenotype. d TLC of five fractions from P. harmala seeds and harmine standard. ***p < 0.001 by unpaired Student’s t-test

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us