Parameters | Patients | IQGAP3 | P | B7-H4 | P | COX-2 | P |
---|---|---|---|---|---|---|---|
n (%) | Mean ± SD, pg/ml | Mean ± SD, ng/ml |  | Mean ± SD, ng/ml | |||
Age (years) | Â | Â | 0.023a | Â | 0.282a | Â | 0.102a |
 ≤ 60 | 53 (44.9) | 300.26 ± 104.31 |  | 99.34 ± 14.23 |  | 47.12 ± 11.23 |  |
 > 60 | 65 (55.1) | 322.47 ± 99.67 |  | 97.25 ± 15.88 |  | 48.38 ± 11.35 |  |
Sex | Â | Â | 0.506a | Â | 0.173a | Â | 0.188a |
 Female | 49 (41.5) | 316.03 ± 104.98 |  | 96.53 ± 13.44 |  | 46.99 ± 12.56 |  |
 Male | 69 (58.5) | 311.54 ± 101.42 |  | 98.96 ± 15.43 |  | 48.32 ± 13.45 |  |
Tumor site | Â | Â | 0.208a | Â | 0.196a | Â | 0.234a |
 Colon | 66 (55.9) | 316.38 ± 99.03 |  | 97.24 ± 15.36 |  | 47.34 ± 12.03 |  |
 Rectum | 52 (44.1) | 312.35 ± 103.54 |  | 95.87 ± 12.14 |  | 48.87 ± 13.67 |  |
Tumor size (cm) | Â | Â | 0.052a | Â | 0.358a | Â | 0.162a |
 ≤ 4 | 63 (53.4) | 311.93 ± 90.17 |  | 98.76 ± 15.67 |  | 47.33 ± 12.28 |  |
 > 4 | 55 (46.6) | 325.00 ± 87.65 |  | 101.11 ± 10.42 |  | 50.12 ± 14.66 |  |
T stage | Â | Â | 0.001b | Â | 0.024b | Â | 0.016b |
 T1 | 22 (18.6) | 180.33 ± 71.10 |  | 81.23 ± 9.32 |  | 37.12 ± 11.02 |  |
 T2 | 32 (27.1) | 185.57 ± 84.10 |  | 89.44 ± 10.53 |  | 45.33 ± 9.89 |  |
 T3 | 34 (28.8) | 272.78 ± 79.20 |  | 96.56 ± 17.53 |  | 51.02 ± 10.17 |  |
 T4 | 30 (25.4) | 382.71 ± 76.76 |  | 103.30 ± 11.88 |  | 53.44 ± 8.76 |  |
N stage |  |  | < 0.001b |  | 0.004b |  | 0.008b |
 N0 | 48 (40.7) | 252.97 ± 88.16 |  | 87.54 ± 12.23 |  | 38.41 ± 9.76 |  |
 N1 | 39 (33.1) | 323.11 ± 80.03 |  | 97.65 ± 14.08 |  | 45.67 ± 11.65 |  |
 N2 | 31 (26.3) | 392.02 ± 88.68 |  | 104.45 ± 9.88 |  | 51.87 ± 10.03 |  |
Differentiation degree | Â | Â | 0.086b | Â | 0.052b | Â | 0.109b |
 Well | 56 (47.5) | 272.75 ± 75.60 |  | 93.33 ± 13.33 |  | 40.89 ± 10.33 |  |
 Moderate | 50 (42.4) | 351.91 ± 90.22 |  | 93.37 ± 12.23 |  | 45.38 ± 11.65 |  |
 Poor | 12 (10.2) | 358.57 ± 91.57 |  | 100.80 ± 13.89 |  | 51.70 ± 11.78 |  |
Retrieved LN | Â | Â | 0.017a | Â | 0.085a | Â | 0.256a |
 ≤ 12 | 61 (51.7) | 354.78 ± 88.75 |  | 97.56 ± 12.80 |  | 47.91 ± 12.36 |  |
 > 12 | 57 (48.3) | 266.63 ± 96.23 |  | 96.38 ± 16.92 |  | 48.56 ± 11.67 |  |
TNM stage |  |  | < 0.001a |  | 0.002a |  | < 0.001a |
 I + II | 48 (40.7) | 270.22 ± 102.70 |  | 88.23 ± 15.67 |  | 39.21 ± 14.22 |  |
 III | 70 (59.3) | 338.86 ± 92.78 |  | 108.12 ± 14.21 |  | 51.87 ± 11.78 |  |