Tumor markers | Â | Control group | CRC group | ||||
---|---|---|---|---|---|---|---|
All | T1 | T2 | T3 | T4 | |||
 | Cases (n) | 85 | 118 | 22 | 32 | 34 | 30 |
IQGAP3 | Levels (mean ± SD, pg/ml) | 191.97 ± 103.96 | 312.68 ± 101.91 | 180.33 ± 71.10 | 185.57 ± 84.10 | 272.78 ± 79.20 | 382.71 ± 76.76 |
P |  | < 0.001# | = 0.284* | = 0.412** | < 0.001*** | < 0.001## | |
CV | 54.2 | 32.6 | 39.4 | 45.3 | 29.0 | 20.1 | |
B7-H4 | Levels (mean ± SD, ng/ml) | 64.78 ± 16.73 | 97.85 ± 15.56 | 81.23 ± 9.32 | 89.44 ± 10.53 | 96.56 ± 17.53 | 103.30 ± 11.88 |
P |  | < 0.001# | = 0.003* | = 0.001** | < 0.001*** | < 0.001## | |
CV | 25.8 | 15.9 | 11.5 | 11.8 | 18.2 | 11.5 | |
COX-2 | Levels (mean ± SD, ng/ml) | 25.78 ± 16.09 | 48.55 ± 13.43 | 37.12 ± 11.02 | 45.33 ± 9.89 | 51.02 ± 10.17 | 53.44 ± 8.76 |
P |  | < 0.001# | = 0.001* | < 0.001** | < 0.001*** | < 0.001## | |
CV | 62.4 | 27.7 | 29.7 | 21.8 | 19.9 | 16.4 | |
CEA | Levels (mean ± SD, ng/ml) | 3.41 ± 1.27 | 6.22 ± 4.49 | 5.34 ± 1.17 | 5.92 ± 1.85 | 6.08 ± 3.82 | 6.34 ± 2.14 |
P |  | < 0.001# | = 0.004* | = 0.001** | < 0.001*** | < 0.001## | |
CV | 37.2 | 72.2 | 21.9 | 31.3 | 62.8 | 33.8 | |
CA19-9 | Levels (mean ± SD, U/ml) | 19.24 ± 10.08 | 29.92 ± 8.97 | 27.19 ± 8.87 | 29.81 ± 9.43 | 30.90 ± 10.16 | 31.5 ± 9.58 |
P |  | < 0.001# | < 0.001* | < 0.001** | < 0.001*** | < 0.001## | |
CV | 52.4 | 30.0 | 32.6 | 31.6 | 32.9 | 30.4 |