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Table 4 Univariate and multivariate Cox regression analysis of overall survival in TNBC

From: Identification of potential key genes and pathways predicting pathogenesis and prognosis for triple-negative breast cancer

Variables

Univariate analysis

Multivariate analysis

HR

95%CI

P-value

HR

95%CI

P-value

Risk score (high vs low)

26.986

(3.487–208.858)

0.002

20.691

(2.551–167.789)

0.005

Age (≥ 54 vs < 54)

1.093

(0.442–2.700)

0.847

   

TNM (I + II, III + IV)

4.283

(1.725–10.633)

0.002

1.131

(0.269–4.757)

0.866

T (T0 + 1, T2 + 3)

1.994

(0.711–5.592)

0.189

   

N (N0 + 1, N2 + 3)

10.753

(3.236–35.733)

< 0.0001

7.736

(1.287–46.486)

0.025

M (M0, M1)

37.815

(3.428–417.110)

0.003

8.963

(0.662–121.313)

0.099

Tumour status (no vs yes)

42.311

(5.453–328.319)

< 0.0001

   

Race (non-white vs white)

0.354

(0.140–0.896)

0.028

0.404

(0.129–1.270)

0.121

Radiation (no vs yes)

6.480

(1.751–23.979)

0.005

   

Targeted (no vs yes)

2.494

(0.534–11.641)

0.245

   
  1. Italic values indicate significance of P value (p < 0.05)
  2. HR: Hazard ratio; CI: confidence interval