Fig. 2
Reversine suppresses the cell proliferation and induces cell apoptosis of 4T1 mouse breast cancer cell lines. a Time- and concentration-dependent changes of cell viability indicating the inhibition of reversion to mouse breast cancer cell line. b Phase-contrast images of 4T1 cell line in the indicated concentrations of reversine for 48 h. c Representative cell apoptosis phase images of the 4T1 cell line in the indicated concentrations of reversine for 48 h. d Related apoptosis rate (%) in 4T1 (n = 3), compared with the control, *p < 0.05, **p < 0.01, ***p < 0.001 (one-way ANOVA), n.s., no significance