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Table 3 Univariate and multivariate analysis for disease-free survival in 161 HR-positive cases

From: LINC00309 is associated with short disease-free survival in breast cancer

 

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI)

pa value

Hazard ratio (95% CI)

pa value

Age

 > 40 vs. ≤ 40

2.312 (1.058–5.054)

0.036

1.532 (0.677–3.465)

0.306

Tumor size

 ≤ 2 vs. > 2

1.535 (0.791–2.978)

0.205

1.149 (0.567–2.327)

0.700

Lymph node status

 Negative vs. positive

1.236 (1.022–1.495)

0.029

1.141 (0.840–1.549)

0.398

Vessel invasion

 Negative vs. positive

2.267 (1.078–4.767)

0.031

1.899 (0.790–4.563)

0.151

Ki-67

 Negative vs. positive

2.230 (1.087–4.575)

0.029

2.478 (1.144–5.368)

0.021

HER-2/neu status

 Negative vs. positive

0.384 (0.141–1.046)

0.061

0.453 (0.160–1.286)

0.137

LINC00309

 Low vs. high

4.505 (1.722–11.785)

0.002

4.159 (1.537–11.251)

0.005

  1. HR hormone-receptor, CI confidence interval, HER-2 human epidermal growth factor receptor 2
  2. ap is based on the Cox regression test
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Cancer Cell International

ISSN: 1475-2867

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