Variables | Group 1 | Group 2 | Group 3 | Group 4 |
---|
Age (mean 62.7Â years) |
 < 63 | 49 | 24 | 34 | 26 |
 ≥ 63 | 56 | 25 | 65 | 37 |
Sex |
 Male | 81 | 39 | 76 | 50 |
 Female | 24 | 10 | 23 | 13 |
Histological type |
 SQC | 27 | 19 | 29 | 25 |
 ADC | 62 | 24 | 56 | 31 |
 LCC | 16 | 6 | 14 | 7 |
 Total | 105a | 49b | 99 | 63 |
- Group 1—Cases of BM from NSCLC
- Group 2—Primary lung carcinoma cases paired to Group 1 cases
- Group 3—Primary lung carcinoma cases without metastasis
- Group 4—Primary lung carcinoma cases with distant metastasis to organs other than brain
- SQC, squamous cell carcinoma; ADC, adenocarcinoma; LCC, large cell carcinoma
- aComposed of 102 cases with open brain surgery and 3 cases with gamma knife radiosurgery (lung primary samples only)
- bNot including 3 patients underwent gamma knife radiosurgery