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Table 3 Univariate and multivariate analyses of prognostic factors for overall survival in CN-AML patients

From: Down-regulation of miR-29c is a prognostic biomarker in acute myeloid leukemia and can reduce the sensitivity of leukemic cells to decitabine

Prognostic factors Univariate analysis Multivariate analysis
Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value
Age 2.080 (1.017–4.255) 0.045 1.125 (0.262–4.825) 0.874
WBC 1.522 (0.852–2.718) 0.049 1.174 (0.305–4.505) 0.816
miR-29c expression 3.546 (1.548–8.130) 0.003 6.897 (1.362 –34.483) 0.020
K/N-RAS mutation (±) 1.395 (0.548–3.550) 0.485
FLT3 mutation (±) 1.185 (0.503–2.793) 0.697
U2AF1 mutation (±) 1.181 (0.574–2.452) 0.651
  1. +: positive; −: negative