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Table 3 Univariate and multivariate analyses of prognostic factors for overall survival in CN-AML patients

From: Down-regulation of miR-29c is a prognostic biomarker in acute myeloid leukemia and can reduce the sensitivity of leukemic cells to decitabine

Prognostic factors

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI)

P value

Hazard ratio (95% CI)

P value

Age

2.080 (1.017–4.255)

0.045

1.125 (0.262–4.825)

0.874

WBC

1.522 (0.852–2.718)

0.049

1.174 (0.305–4.505)

0.816

miR-29c expression

3.546 (1.548–8.130)

0.003

6.897 (1.362 –34.483)

0.020

K/N-RAS mutation (±)

1.395 (0.548–3.550)

0.485

–

–

FLT3 mutation (±)

1.185 (0.503–2.793)

0.697

–

–

U2AF1 mutation (±)

1.181 (0.574–2.452)

0.651

–

–

  1. +: positive; −: negative