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Fig. 1 | Cancer Cell International

Fig. 1

From: Smoking history influences the prognostic value of peripheral naïve CD4+ T cells in advanced non-small cell lung cancer

Fig. 1

a Comparisons of naïve cells and memory T cells between 98 advanced NSCLC patients and 62 healthy controls. NSCLC patients had low levels of naïve CD4+ T (P < 0.001) and CD4+ naïve/memory ratio (P < 0.001), and high levels of memory CD4+ T (P < 0.001), memory CD8+ T (P = 0.001), and naïve CD8/CD4 ratio (P < 0.001) than healthy controls. b Comparisons of naïve cells and memory T cells between 55 ever smokers and 43 never smokers. Ever smokers expressed low levels of naïve CD4+ T (P = 0.005), naïve CD8+ T (P = 0.031), CD4+ naïve/memory ratio (P = 0.020) and CD8+ naïve/memory ratio (P = 0.019), and high memory CD4+ T (P = 0.004), memory CD8+ T (P = 0.034) counts, and naïve CD8/CD4 ratio (P = 0.020) than never smokers. Error bar represents standard deviation (SD). *P < 0.05, **P < 0.01, ***P < 0.001, two-sided paired Student’s t-test (a, b)

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Cancer Cell International

ISSN: 1475-2867

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