Table 2 Correlations the clinical characteristics among CNR1 between HCC with or without cirrhosis in TCGA
Variables | N | Non-cirrhotic HCC | N | Cirrhotic HCC | ||
|---|---|---|---|---|---|---|
CNR1 | CNR1 | |||||
Low/high expression case (n) | p value | Low/high expression case (n) | p value | |||
Gender | ||||||
 Male | 82 | 44/38 | 0.282 | 61 | 31/30 | 0.635 |
 Female | 50 | 22/28 | 18 | 8/10 | ||
Age at diagnosis | ||||||
 ≥ 60 | 80 | 38/42 | 0.476 | 36 | 17/19 | 0.650 |
 < 60 | 52 | 28/24 | 42 | 22/20 | ||
 NA | 0 | 0 | 1 | 0/1 | ||
T stage | ||||||
 T1/T2 | 97 | 48/49 | 1.000 | 70 | 35/35 | 0.712 |
 T3/T4 | 33 | 17/16 | 8 | 3/5 | ||
 TX | 1 | 1/0 | 0 | 0/0 | ||
 NA | 1 | 0/1 | 1 | 1/0 | ||
N stage | ||||||
 N0 | 91 | 49/42 | 0.259 | 57 | 29/28 | 1.000 |
 N1 | 1 | 0/1 | 1 | 0/1 | ||
 NX | 40 | 17/23 | 20 | 10/10 | ||
 NA | 0 | 0/0 | 1 | 0/1 | ||
M stage | ||||||
 M0 | 90 | 46/44 | 0.529 | 62 | 31/31 | 0.830 |
 M1 | 4 | 3/1 | 0 | 0/0 | ||
 MX | 38 | 17/21 | 17 | 8/9 | ||
Pathologic stage | ||||||
 I/II | 91 | 44/47 | 0.755 | 67 | 35/32 | 0.478 |
 III/IV | 33 | 17/16 | 9 | 3/6 | ||
 NA | 8 | 5/3 | 3 | 1/2 | ||
Vascular invasion | ||||||
 None | 87 | 38/49 | 0.127 | 52 | 26/26 | 0.900 |
 Micro | 33 | 18/15 | 22 | 10/12 | ||
 Macro | 6 | 5/1 | 2 | 1/1 | ||
 NA | 6 | 5/1 | 3 | 2/1 | ||
HBV infection | ||||||
 Yes | 38 | 25/13 | 0.036 | 36 | 20/16 | 0.358 |
 No | 88 | 40/48 | 40 | 18/22 | ||
 NA | 6 | 1/5 | 3 | 1/2 | ||
HCV infection | ||||||
 Yes | 14 | 6/8 | 0.488 | 20 | 13/7 | 0.118 |
 No | 112 | 59/53 | 56 | 25/31 | ||
 NA | 6 | 1/5 | 3 | 1/2 | ||