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Fig. 3 | Cancer Cell International

Fig. 3

From: Interfering cellular lactate homeostasis overcomes Taxol resistance of breast cancer cells through the microRNA-124-mediated lactate transporter (MCT1) inhibition

Fig. 3

MiR-124 is negatively correlated with Taxol resistance. a BT474, b SKBR3 and c MCF7 cells were treated with or without Taxol at the indicated concentrations for 48 h, the expressions of miR-124 were detected by qRT-PCR. d Expressions of miR-124 were detected from human primary breast cancer tissues and their matched adjacent normal breast tissues by qRT-PCR. e MCF7 cells were transfected with control miRNAs or miR-124 for 48 h, followed by the measurements of cell viability at 0, 2, 4 and 6 days. f Expressions of miR-124 from MCF7 parental cells and Taxol resistant cells were measured by qRT-PCR. *p < 0.05; **p < 0.01; ***p < 0.001

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