From: Modulation of doxorubicin-induced expression of the multidrug resistance gene in breast cancer cells by diltiazem and protection against cardiotoxicity in experimental animals
Treatment
Glutathione peroxidase (U/ml)
(48 h)
(72 h)
Control
9.6 ± 0.48
9.7 ± 0.72
DIL (4 mg/kg i.p.)
9.8 ± 0.72
10.1 ± 0.46
DOX (15 mg/kg, i.p.)
5.4 ± 0.33a
4.8 ± 0.91a
DOX + DIL (administrated simultaneously)
9.4 ± 0.86b
9.5 ± 0.42b