Fig. 2
From: Mfn2 inhibits proliferation and cell-cycle in Hela cells via Ras-NF-κB signal pathway
The effect and the signal pathway of Mfn2 on cell-cycle in Hela cells. a HeLa cells were incubated with Ad-Mfn2 for 60 h. Cells stained with Cell-Cycle assay after incubated with two concentrations (100 pfu/cell) of Adv-Mfn2 were measured by flow cytometry. b The percentage of every phase of cell-cycle after HeLa cells being treated with indicated concentrations of Adv-Mfn2 or Adv-control was calculated. c Adv-Mfn2 increased the expression of Cyclin D1 by western blot. Beta-actin was used as reference. d Expressions of Ras and Myc after HeLa cells being treated with Adv-Mfn2. GAPDH was used as reference. e Expressions of STAT3 and NF-κB after HeLa cells being treated with Adv-Mfn2. GAPDH was used as reference