Fig. 7

Final models show differences in fates between K−MN and K+MN in mitois. Based on the study, fates of of K−MN and K+MN were included in final models. a The fates of K−MN in mitosis. (1) The cycle of K−MN → CF (Chromosome fragment) → K−MN. If K−MN-bearing cells enter mitosis, major of K−MNi transform into CFs, which CFs evolve into K−MNi in daughter cells. (2) Disappearance. When K−MN-bearing cells enter mitosis, minor of K−MNi disappear in mitosis. b The fates of K+MN in mitosis. (1) Reincorporation. If K+MN-bearing cells enter mitosis, major of K+MNi reincorporate into main nuclei and no K+MNi emerge in daughter cells. (2) The cycle of K+MN → K+LC → K+MN. Minor of K+MNi transform into K+LCs, which evolve into K+MNi in daughter cells. The models show differences in fates between K−MN and K+MN. And kinetochores determine the fates of K−MN and K+MN in mitosis