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Table 4 Multivariate COX regression for prognostic features of gastric cancer patients

From: Multivariate analysis of clinicopathological and prognostic significance of miRNA 106b~25 cluster in gastric cancer

Features

β

SE

Wald

df

P

HR (95% CI)

T stage

 T1, T2

− 0.916

0.341

7.229

1

0.007

0.400 (0.205–0.780)

 T3, T4

      

N stage

 N0

0.612

0.714

0.734

1

0.392

1.844 (0.455–7.470)

 N1–N3

      

TNM stage

 I, II

0.703

0.446

2.485

1

0.115

2.019 (0.843–4.839)

 III, IV

      

Tumor size

 < 5

0.832

0.494

2.839

1

0.092

2.297 (0.873–6.042)

 > 5

      

Plasma miR 106b

 Low

− 0.990

0.489

4.099

1

0.043

0.371 (0.142–0.969)

 High

      

Plasma miR 93

 Low

− 0.125

0.403

0.096

1

0.757

0.882 (0.400–1.946)

 High

      

Plasma miR 25

 Low

0.555

0.407

1.861

1

0.172

1.742 (0.785–3.866)

 High

      

Tumor miR 106b

 Low

0.220

0.377

0.340

1

0.560

1.246 (0.595–2.612)

 High

      

Tumor miR 93

 Low

− 1.220

0.403

9.162

1

0.002

0.295 (0.134–0.650)

 High

      

Tumor miR 25

 Low

− 0.029

0.477

0.004

1

0.951

0.971 (0.381–2.473)

 High

      
  1. To get adjusted hazard ratios, COX regression was applied for adjusting significant covariate in Kaplan–Meier prognostic analysis
  2. β regression coefficient, SE standard error, Wald wald Chi square; df degree of freedom, HR hazard ratio