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Fig. 5 | Cancer Cell International

Fig. 5

From: miR-125b-5p inhibits cell proliferation, migration, and invasion in hepatocellular carcinoma via targeting TXNRD1

Fig. 5

TXNRD1 overexpression counteracts miR-125b-5p-mediated attenuation of HCC cell migration and invasion. a qRT-PCR- and b western blotting-based confirmation of miR-125b-5p and TXNRD1 overexpression. pENTER (empty plasmid) was used as a control to determine TXNRD1 overexpression (n = 3; one-way ANOVA and Dunnett’s multiple comparison test). ch TXNRD1 overexpression abolished miR-125b-5p-mediated repression of c, d HCC cell proliferation according to EdU-incorporation assay (n = 3; one-way ANOVA and Dunnett’s multiple comparison test) and eh migration and invasion in HCC cells (n = 3; one-way ANOVA and Dunnett’s multiple comparison test). *P < 0.05; **P < 0.01; ***P < 0.001

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