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Table 1 Clinicopathological characteristics of the 74 patients with HGSC

From: LPAR1 regulates the development of intratumoral heterogeneity in ovarian serous cystadenocarcinoma by activating the PI3K/AKT signaling pathway

 

Mean or number

Range or percentage

Age at diagnosis (years)

53.41 ± 9.29

34–76

 Menopausal status

  Pre-menopausal

23

31.1%

  Post-menopausal

51

68.9%

 Family history of cancer

  Yes

6

8.1%

  No

68

91.9%

Preoperative CA125 levels (IU/ml)

2005.42 ± 3137.71

15–17,980

 FIGO stage

  Stage I

10

13.5%

  Stage II

6

8.1%

  Stage III

52

70.3%

  Stage IV

6

8.1%

 Lymphatic metastasis

  Yes

28

37.8%

  No

46

62.2%

 Cytoreductive surgery

  Residual tumor ≤ 1 cm

53

71.6%

  Residual tumor > 1 cm

22

29.7%

 Current status

  NED

25

33.8%

  AWD

19

25.7%

  DOD

30

40.5%

  1. HGSC high-grade sercous carcinoma, FIGO International Federation of Gynecology and Obstetrics, NED no evidence of disease, AWD alive with disease, DOD die of disease