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Fig. 3 | Cancer Cell International

Fig. 3

From: miR-450b-5p loss mediated KIF26B activation promoted hepatocellular carcinoma progression by activating PI3K/AKT pathway

Fig. 3

Suppression of KIF26B inhibits proliferation rate and invasion ability of HCC cells in vitro. a Expression difference of KIF26B between HCC tissues and adjacent non-tumor tissues was showed. b Protein level of KIF26B between normal hepatocytes cell lines and HCC cell lines was compared. And transfect efficiency of KIF26B shRNA in Hep-3B and HCC-LM3 cells was verified in protein level. ce Cell viability of Hep-3B and HCC-LM3 cells under treatment of KIF26B shRNA and negative control in 24 h, 48 h and 72 h. f, g Cell proliferation rate and invasion ability of Hep-3B and HCC-LM3 cells under treatment of KIF26B shRNA and negative control. h Tumor formation ability of HCC cells with KIF26B shRNA and Negative control was compared in vitro. Mean ± SD, *p < 0.05, unpaired Student’s t test or one-way ANNOVA followed by multiple t test

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