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Fig. 6 | Cancer Cell International

Fig. 6

From: Upregulation of circFLNA contributes to laryngeal squamous cell carcinoma migration by circFLNA–miR-486-3p-FLNA axis

Fig. 6

FLNA was up-regulated in LSCC tissues and correlated with poor prognosis. a qRT-PCR detected NPL4 mRNA expression in LSCC tissues (n = 39) and adjacent normal tissues (n = 39). *P < 0.05 vs. adjacent normal tissues. b FLNA mRNA expression in LSCC tumor and normal tissues from the TCGA database. c LSCC patients divided into two groups, with lymph node metastasis group or without lymph node metastasis group. qRT-PCR was used to detected FLNA mRNA expression in two groups. *P < 0.05 vs. group without lymph node metastasis. d Pearson correlation was used to analyze the relationships between FLNA mRNA and circFLNA (R = 0.3945, P = 0.0255). e NPL4 mRNA expression in Kaplan–Meier analysis of overall survival stratified by low and high FLNA expression (P = 0.0225)

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