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Fig. 8 | Cancer Cell International

Fig. 8

From: Long non-coding RNA LINC00485 acts as a microRNA-195 sponge to regulate the chemotherapy sensitivity of lung adenocarcinoma cells to cisplatin by regulating CHEK1

Fig. 8

CHEK1 reverses the impacts of miR-195 on LAC cells. a, b The protein bands and expression of CHEK1, Bcl-2, VEGF, HIF-1α and Bax in A549 cells; c the colony formation of A549 cells; d the apoptosis of A549 cells; e, f the protein bands and expression of CHEK1, Bcl-2, VEGF, HIF-1α and Bax in H1299 cells; g the colony formation of H1299 cells; h the apoptosis of H1299 cells; *p < 0.05 vs. cells co-transfected with NC + vector. Differences among multiple groups were analyzed by one-way ANOVA. All the experiments were detected 3 times independently, and the results were expressed as mean ± standard deviation

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