Fig. 1From: Cell death-related molecules and biomarkers for renal cell carcinoma targeted therapyInteractions between VHL, HIF and the NF-κB signaling pathway. Inactivation of VHL initiates multiple downstream signaling pathways, including the HIF/VEGF and NF-κB transcription factor/HIF pathways, which become the basis of the crosstalk between cell death-related molecules, immunotherapy and targeted therapyBack to article page