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Fig. 5 | Cancer Cell International

Fig. 5

From: miR-145 sensitizes esophageal squamous cell carcinoma to cisplatin through directly inhibiting PI3K/AKT signaling pathway

Fig. 5

miR-145 facilitated DDP-induced G1 arrest by decreasing AKT3 in ESCC cells. a Cell cycle was analyzed with flow cytometry in EC109 and KYSE-30 exposed to DDP after transfection with miR-145 mimics, sh-AKT3, or miR-145 mimcis + pcDNA3.1-AKT3. b Statistics of cell number in G1, S and G2 stages. All the results were shown as mean ± SD (n = 3), which were three separate experiments performed in triplicate. *p < 0.05 and **p < 0.01

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Cancer Cell International

ISSN: 1475-2867

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