Table 1 Correlation between the expression levels of miR-145 and the clinicopathological characteristics of ESCC patients
Clinical parameters | Cases (n) | miR-145 expression | P-value (*P < 0.05) | |
|---|---|---|---|---|
High (n) | Low (n) | |||
Gender | ||||
Male | 21 | 9 | 12 | 0.232 |
Female | 9 | 6 | 3 | |
Age | ||||
< 60 | 17 | 7 | 10 | 0.269 |
≥ 60 | 13 | 8 | 5 | |
Tumor location | ||||
Upper | 7 | 3 | 4 | 0.753 |
Middle | 12 | 7 | 5 | |
Lower | 11 | 5 | 6 | |
Tumor size (cm) | ||||
< 3 | 16 | 10 | 6 | 0.143 |
≥ 3 | 14 | 5 | 9 | |
Differentiation grade | ||||
Well-moderate | 23 | 12 | 11 | 0.666 |
Poor-undifferentiation | 7 | 3 | 4 | |
Lymph node metastasis | ||||
Negative | 15 | 10 | 5 | 0.068 |
Positive | 15 | 5 | 10 | |
TNM stage | ||||
I–II | 14 | 10 | 4 | 0.028* |
III–IV | 16 | 5 | 11 | |