Fig. 4

miR-200c-3p inhibits expression of SOX2 and inactivates the Wnt/β-catenin pathway. a Expression of β-catenin and GSK3β mRNA after miR-200c-3p-mimics transfection into OS-RC-2 cells. b Expression of SOX2, β-catenin and GSK3β protein after miR-200c-3p-mimics transfection into OS-RC-2 cells. c Expression of β-catenin and GSK3β mRNA after miR-200c-3p-mimics transfection into A498 cells. d Expression of SOX2, β-catenin and GSK3β protein after miR-200c-3p-inhibitors and si-SOX2 transfection into A498 cells; N = 5; *P < 0.05 vs the blank group