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Fig. 3 | Cancer Cell International

Fig. 3

From: CDK5 neutralizes the tumor suppressing effect of BIN1 via mediating phosphorylation of c-MYC at Ser-62 site in NSCLC

Fig. 3

Effects of CDK5 on the malignant behaviors of NSCLC cells. a The effect of CDK5 knockdown on the growth ability of H460 cells. b The effect of CDK5 knockdown on the migration ability of H460 cells. c The effect of CDK5 knockdown on the invasion ability of H460 cells. d The effect of CDK5 knockdown on the expression of EMT-related proteins in H460 cells, GAPDH as control. e The effect of CDK5 overexpression on the growth ability of PC9 cells. f The effect of CDK5 overexpression on the migration ability of PC9 cells. g The effect of CDK5 overexpression on the invasion ability of PC9 cells. h The effect of CDK5 overexpression on the expression of EMT-related proteins in PC9 cells, GAPDH as control. Significant P-values marked by asterisk: *P < 0.05

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Cancer Cell International

ISSN: 1475-2867

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