Table 2 Key GO biological processes and KEGG pathways

Down

KEGG_PATHWAY

hsa03013:RNA transport

RPP38, NXT1, RPP25, PHAX, ELAC1, EIF1, PYM1, GEMIN6, POP7

hsa04115:p53 signaling pathway

BID, SIAH1, PMAIP1, IGFBP3, TP53AIP1

hsa05202:Transcriptional misregulation in cancer

CEBPA, CEBPB, HIST1H3E, IGFBP3, MYC, ATF1, DDIT3, ETV4

GO_BP

GO:0070125 ~ mitochondrial translational elongation

MRPS26, MRPS34, MRPL12, MRPS33, TSFM, MRPS12, MRPL36, MRPS6, MRPL58, MRPL44

GO:0070126 ~ mitochondrial translational termination

MRPS26, MRPS34, MRPL12, MRPS33, MRPS12, MRPL36, MRPS6, MRPL58, MRPL44

GO:0042273 ~ ribosomal large subunit biogenesis

WDR74, NOP16, NIP7, RRS1, YAE1D1

GO:0006364 ~ rRNA processing

RPP38, RPP25, RRP1, EXOSC4, BYSL, EXOSC5, PNO1, NOB1, RPS15A, DIEXF, LTV1, MRTO4, MRM3

GO:0042102 ~ positive regulation of T cell proliferation

HAVCR2, HES1, TNFSF13B, ZP3, CD274, IL12A

GO:0070059 ~ intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

CEBPB, CHAC1, TRIB3, PMAIP1, DDIT3

Up

KEGG_PATHWAY

hsa03320:PPAR signaling pathway

ACOX2, ACSL1, EHHADH, RXRA, SCD, FADS2, GK, SCD5, ACSL3, ACAA1

hsa04115:p53 signaling pathway

CDKN1A, CCNB2, CCND2, RRM2, APAF1, CCNG2, SESN1, GTSE1, SESN3

hsa04144:Endocytosis

FGFR2, PRKCZ, LDLR, RAB5B, CYTH2, EEA1, PSD2, CLTC, GBF1, TFRC, CXCR4, VPS35, WIPF1, BIN1, CLTCL1, HSPA8, SH3GL2, IQSEC2, F2R

hsa04912:GnRH signaling pathway

MAPK14, ADCY5, MAP3K1, CALM3, PRKACA, PRKACB, CACNA1F, CACNA1D, PRKCB

hsa04722:Neurotrophin signaling pathway

MAGED1, RPS6KA2, MAPK14, BCL2, MAP3K1, CALM3, SORT1, NGFR, KIDINS220, PIK3R3

GO_BP

GO:0007155 ~ cell adhesion

NRP2, MTSS1, ACHE, PCDHA2, L1CAM, PCDHGC3, PCDHAC1, COMP, COL12A1, CD24, LOXL2, BOC, APBA1, TYRO3, FLOT2, PODXL, MFGE8, TINAGL1, CTNNA1, COL16A1, MCAM, COL5A1, NCAM1, JUP, DSG2, CNTN1, SUSD5, ADAM12, NCAN, CD226, NTM

GO:0051301 ~ cell division

SEPT4, SEPT1, GNAI2, NEK2, CLTC, CCNG2, CD2AP, SPC25, CDCA8, NCAPH, NCAPG, NCAPG2, CENPC, BUB1, CABLES2, TUBA1A, TUBA1B, CCNA2, CDK14, KIF11, TPX2, CDC20, RB1, KNSTRN, CDC25C, CDC25B, CCNB2, CCND2, CDCA7L, MAPRE2

GO:0000281 ~ mitotic cytokinesis

KIF4A, NUSAP1, ANLN, CEP55, RACGAP1, KIF20A

GO:0048873 ~ homeostasis of number of cells within a tissue

CORO1A, BCL2, ILDR2, F2R, ADD1, FLT3LG

GO:0007265 ~ Ras protein signal transduction

ZNF304, CDKN1A, DOK3, MAPK14, IQGAP3, RB1, CCNA2, DHCR24

GO:0032012 ~ regulation of ARF protein signal transduction

GBF1, CYTH2, PSD2, IQSEC2

GO:0045746 ~ negative regulation of Notch signaling pathway

PEAR1, BEND6, GDPD5, DLK2, BMP7