Table 2 The relationship between TOP2A and NSCLC clinical pathological parameters
From: Prognostic significance of TOP2A in non-small cell lung cancer revealed by bioinformatic analysis
Group | TOP2A | P value | |
|---|---|---|---|
− | + | ||
Histological subtype | |||
Adenocarcinoma | 48 (78.7%) | 13 (21.3%) | P = 0.000 |
Squamous carcinoma | 20 (43.5%) | 26 (56.5%) | |
Gender | |||
Male | 35 (51.5%) | 33 (48.5%) | P = 0.001 |
Female | 33 (84.6%) | 6 (15.4%) | |
Age | |||
< 55 | 15 (75.0%) | 5 (25.0%) | P = 0.238 |
≥ 55 | 53 (60.9%) | 34 (39.1%) | |
Smoke | |||
No | 34 (79.1%) | 9 (20.9%) | P = 0.006 |
Yes | 34 (53.1%) | 30 (46.9%) | |
Location | |||
Upper lobe | 31 (58.5%) | 22 (41.5%) | P = 0.521 |
Middle lobe | 7 (63.6%) | 4 (36.4%) | |
Lower lobe | 30 (69.8%) | 13 (30.2%) | |
Tumor size | |||
< 2 cm | 13 (76.5%) | 4 (23.5%) | P = 0.228 |
≥ 2 cm | 55 (61.6%) | 35 (38.9%) | |
Differentiation poorly | |||
Differentiated | 13 (54.2%) | 11 (45.8%) | P = 0.182 |
Moderately differentiated | 47 (63.5%) | 27 (36.5%) | |
Well differentiated | 8 (88.9%) | 1 (11.1%) | |
p-Stage | |||
I | 22 (64.7%) | 12 (35.3%) | P = 0.907 |
II | 19 (67.9%) | 9 (32.1%) | |
III | 11 (57.9%) | 8 (42.1%) | |
IV | 16 (61.5%) | 10 (38.5%) | |
Invasion of capsule | |||
No | 42 (68.9%) | 19 (31.1%) | P = 0.190 |
Yes | 26 (56.5%) | 20 (43.5%) | |
Invasion of bronchial stump | |||
No | 63 (65.6%) | 33 (34.4%) | P = 0.188 |
Yes | 5 (45.5%) | 6 (54.5%) | |
LN metastasis | |||
− | 46 (62.2%) | 28 (37.8%) | P = 0.656 |
+ | 22 (66.7%) | 11 (33.3%) | |