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Table 5 KEGG signaling pathways centered on TOP2A

From: Prognostic significance of TOP2A in non-small cell lung cancer revealed by bioinformatic analysis

Term description

Counts

Background gene counts

FDR

Matching proteins in the network

Cell cycle

4

123

5.57E−06

BUB1, CCNB2, CDC20, CDK1

Oocyte meiosis

4

116

5.57E−06

BUB1, CCNB2, CDC20, CDK1

Progesterone-mediated oocyte maturation

3

94

8.19E−05

BUB1, CCNB2, CDK1

p53 signaling pathway

2

68

0.0022

CCNB2, CDK1

Ubiquitin mediated proteolysis

2

134

0.0066

CDC20, UBE2C

Cellular senescence

2

156

0.0074

CCNB2, CDK1

Viral carcinogenesis

2

183

0.0086

CDC20, CDK1

HTLV-I infection

2

250

0.0137

CCNB2, CDC20