Table 2 Multivariate analysis of prognostic variables including classical prognostic factors and CD47 for disease-free survival in breast cancer patients
From: Combined high expression of CD47 and CD68 is a novel prognostic factor for breast cancer patients
Variables | Hazard ratio | 95% CI | P | |
|---|---|---|---|---|
Lower | Upper | |||
TNM stage (II + I vs. III) | 1.852 | 1.116 | 3.075 | 0.017 |
Histological grade (grade 1 + 2 vs. grade 3) | 3.661 | 2.250 | 5.958 | < 0.001 |
Lymph node metastasis (no vs. yes) | 2.769 | 1.402 | 5.472 | 0.003 |
ER status (negative vs. positive) | 0.675 | 0.369 | 1.236 | 0.203 |
PR status (negative vs. positive) | 1.133 | 0.649 | 1.978 | 0.661 |
HER2 gene (non-amplification vs. amplification) | 1.812 | 1.120 | 2.932 | 0.015 |
CD47 (low expression vs. high expression) | 1.732 | 0.970 | 3.093 | 0.063 |